Seafood lasagna is one of those delightful dishes that makes you feel like you’ve traveled to the coast, even if you’re just cooking at home. Imagine layers of creamy goodness, plump shrimp, and sweet crab nestled between sheets of pasta, all brought together by a savory sauce. It’s the kind of comfort food that warms your heart and lifts your spirits. So, if you’re ready to impress your family or friends, grab your apron! I’ll guide you through this tasty adventure step-by-step. Not only is this recipe filled with rich flavors, but it also uses oven-ready lasagna noodles for added convenience. Plus, the infusion of clam juice in the sauce deepens the taste, making every bite a little piece of heaven. So let’s gather our ingredients and get started on this amazing seafood lasagna that will leave everyone asking for seconds!
Thank you for reading this post, don't forget to subscribe!Why This Recipe Works
One of the best things about this seafood lasagna recipe is how it combines the rich flavors of seafood with creamy layers of deliciousness. The marriage of shrimp and crab offers a complex taste that stands out. Using oven-ready lasagna noodles simplifies the process. You skip the boiling step, making this dish easy to prepare. Plus, the added clam juice in the sauce rounds out the flavor profile, giving it a depth that’s hard to resist.
Why You’ll Love This Seafood Lasagna
This dish is a journey for seafood lovers. The variety of textures and tastes pleases the palate, and it’s visually stunning, making it perfect for gatherings or special occasions. You’ll impress your guests with your culinary skills, while also ensuring it’s easy to follow so that anyone can make it. Whether you’re an experienced cook or a beginner, you’ll find success with this seafood lasagna.

Ingredients
- 3 Tablespoons unsalted butter
- 3 Tablespoons all-purpose flour
- 2 cups heavy cream
- 1 cup clam juice
- 1/2 teaspoon garlic powder
- 1/2 teaspoon onion powder
- 1/4 teaspoon ground nutmeg (optional)
- 1 teaspoon Italian seasoning
- ½ cup grated parmesan cheese
- 1 teaspoon kosher salt
- ½ teaspoon black pepper
- 2 Tablespoons olive oil
- 1 medium onion, finely chopped
- 8 ounces small shrimp, peeled and deveined
- 8 ounces lump crab meat
- 1/4 cup chopped fresh parsley (plus more for garnish)
- 9-12 oven-ready lasagna noodles
- 4 cups shredded mozzarella cheese
Prepare the Creamy Sauce

Melting the Butter and Cooking the Flour
Start by placing a medium saucepan over medium heat. Melt the unsalted butter, allowing it to bubble just a bit. Once it’s melted, whisk in the flour until the mixture becomes smooth and bubbly. Let it cook for about a minute.
Adding Cream and Clam Juice
Next, slowly pour in the heavy cream and clam juice while whisking constantly. This prevents those pesky lumps from forming. Keep stirring for around 5-7 minutes until the mixture thickens nicely.
Infusing the Sauce with Flavor
Now, it’s time to bring out the flavors! Stir in garlic powder, onion powder, optional nutmeg, Italian seasoning, and ½ cup of parmesan cheese. Season with kosher salt and black pepper before removing it from the heat.
Cook the Seafood Filling
Sautéing the Onion
In another skillet, heat the olive oil over medium heat. Toss in the finely chopped onion and sauté for about 3-4 minutes until it softens and turns fragrant.
Cooking the Shrimp
Next, add the shrimp to the skillet. Cook for about 2-3 minutes until they turn pink and tender. At this point, gently fold in the crab meat and chopped parsley, mixing everything well.
Assemble the Seafood Lasagna
Layering the Ingredients
Grab a greased 9×13-inch baking dish and spread a thin layer of the creamy sauce over the bottom. Then, place enough lasagna noodles to cover the base, overlapping them slightly if needed.
Creating the Layers
Now for the fun part! Spread a third of your seafood mixture over the noodles, followed by a third of the sauce, and then add 1/3 of the shredded mozzarella cheese. Repeat this process two more times. Finally, finish with a last layer of noodles, pour the remaining sauce on top, and sprinkle with the rest of the mozzarella.
Bake the Lasagna
Covering and Baking
To ensure even cooking, cover the dish tightly with aluminum foil, making sure it doesn’t touch the cheese. Pop it into a preheated oven at 350°F (175°C) for 30 minutes.
Final Baking for a Golden Finish
After that, carefully remove the foil and let it bake uncovered for another 15-20 minutes. You want the top to turn golden and bubbly. When it’s done, let it rest for about 10 minutes before serving. Garnish with fresh parsley for a nice touch!
Serving Suggestions
To make your meal even better, consider pairing your seafood lasagna with a crisp white wine, like Sauvignon Blanc. A fresh garden salad or some garlic bread on the side complements the dish perfectly, enhancing your dining experience.
Tips for Success
For a hearty lasagna, be generous with your layers. Also, letting the dish rest before cutting it will help set everything, making for a prettier presentation.
Variations
Feel free to get creative! You can substitute with different seafood like scallops or lobster. Adding fresh spinach or zucchini not only boosts nutrition but also adds a lovely color to your dish.
Storage Tips
If you have leftovers, store them covered in the fridge; they can last up to 3 days. If you’d like to prepare this dish ahead of time, freezing it before baking is a great option for a quick and easy meal later.

FAQs
1. Can I use regular lasagna noodles?
Yes, just remember to boil them beforehand, which requires adjusting the cooking time.
2. Is it possible to make this ahead of time?
Absolutely! You can assemble the lasagna, refrigerate it, and then bake it when you’re ready to serve.
3. What if I don’t like crab?
No worries! You can replace it with more shrimp or try other seafood varieties based on what you prefer.
4. Can I make a vegetarian version?
Yes! Just use hearty vegetables with a creamy white sauce as a delicious alternative.
5. How do I reheat leftovers?
Reheat in the oven at 350°F (175°C) until heated through, which should take about 20 minutes.
Seafood lasagna is more than just a meal; it’s an experience that brings warmth and comfort to any table. With its rich and savory layers, it promises a feast that captivates both eyes and taste buds. Whether for a special celebration or a cozy dinner at home, this recipe is one you’ll cherish and share for years to come. Enjoy every moment of cooking and savor the delicious outcome!
Print
Seafood Lasagna
This seafood lasagna offers a delightful combination of creamy layers with shrimp and crab, making it a perfect dish for gatherings or special occasions. It’s easy to prepare, tastes divine, and is sure to impress anyone at your table.
- Total Time: 1 hour 10 minutes
- Yield: 6 servings 1x
Ingredients
- 3 Tablespoons unsalted butter
- 3 Tablespoons all-purpose flour
- 2 cups heavy cream
- 1 cup clam juice
- 1/2 teaspoon garlic powder
- 1/2 teaspoon onion powder
- 1/4 teaspoon ground nutmeg (optional)
- 1 teaspoon Italian seasoning
- ½ cup grated parmesan cheese
- 1 teaspoon kosher salt
- ½ teaspoon black pepper
- 2 Tablespoons olive oil
- 1 medium onion, finely chopped
- 8 ounces small shrimp, peeled and deveined
- 8 ounces lump crab meat
- 1/4 cup chopped fresh parsley (plus more for garnish)
- 9–12 oven-ready lasagna noodles
- 4 cups shredded mozzarella cheese
Instructions
- Melt butter in a medium saucepan over medium heat, whisk in flour, and cook until bubbly.
- Slowly pour in cream and clam juice, whisking until thickened.
- Stir in seasonings and cheese, then remove from heat.
- In a skillet, heat olive oil and sauté onion until soft.
- Add shrimp and cook until pink, then fold in crab and parsley.
- Grease a baking dish, layer sauce, noodles, seafood mixture, and mozzarella, repeating layers.
- Cover with foil and bake at 350°F for 30 minutes, uncover and bake for another 15-20 minutes until golden.
Notes
Let the lasagna rest for 10 minutes before serving for better presentation.
Feel free to experiment with different seafood or add vegetables like spinach.
Store leftovers in the fridge for up to 3 days.
- Prep Time: 20 minutes
- Cook Time: 50 minutes
- Category: Main Course
- Method: Baking
- Cuisine: Italian
Nutrition
- Calories: 450
- Sugar: 3
- Sodium: 600
- Fat: 25
- Saturated Fat: 15
- Unsaturated Fat: 5
- Trans Fat: 0
- Carbohydrates: 35
- Fiber: 2
- Protein: 25
- Cholesterol: 90






